How gum disease bacteria may contribute to memory loss

Recent research has uncovered a startling connection between oral health and brain function, revealing that certain bacteria responsible for gum disease may play a key role in the development of Alzheimer’s disease. A study conducted by the University of Bergen in Norway found clear DNA-based proof that Porphyromonas gingivalis (P. gingivalis)—a harmful bacterium commonly associated with periodontitis—can migrate from the mouth to the brain, where it may contribute to the destruction of nerve cells.

The creepy crawler in the brain

Alzheimer’s disease

P. gingivalis doesn’t just stay in the mouth. This dangerous bacterium can travel through the bloodstream and nerve pathways, making its way into the brain. Once there, it releases toxic enzymes and proteins that trigger inflammation and the breakdown of neurons. The death of these brain cells can contribute to memory loss, cognitive decline, and, ultimately, Alzheimer’s disease.

Mounting evidence: Oral health and cognitive decline

The Norwegian study isn’t the only research linking gum disease to neurodegenerative conditions. A 2014 study from the UK also identified the presence of P. gingivalis in the brains of Alzheimer’s patients. The researchers concluded that repeated exposure to this bacterium and its toxic by-products could provoke an ongoing immune response, leading to chronic inflammation and the progressive destruction of brain cells.

While Alzheimer’s is a complex disease with multiple contributing factors, the presence of P. gingivalis appears to significantly increase the risk and accelerate its progression. This makes oral health not just a matter of preserving your teeth and gums, but potentially safeguarding your long-term cognitive health as well.

Eliminating P. gingivalis before it spreads

Instead of waiting for a cure, the best approach is prevention. If P. gingivalis is a trigger for Alzheimer’s and other systemic diseases, stopping it at its source—the mouth—is crucial. Here’s how you can reduce your risk:

✔ Practice excellent oral hygiene: Brush twice a day, floss daily, and use an antibacterial mouthwash to keep harmful bacteria in check.

✔ Schedule regular dental checkups: Routine visits allow your dentist to detect early signs of gum disease and provide treatments to prevent bacterial overgrowth.

✔ Consider Oral Pathogen Testing: Advanced diagnostic tools can identify harmful bacteria like P. gingivalis before they cause severe damage, allowing for targeted treatment.

✔ Maintain a healthy diet: Reduce sugar intake and consume fibre-rich foods to nourish beneficial bacteria and support a balanced oral microbiome.

✔ Stay hydrated and avoid dry mouth: Saliva naturally helps wash away harmful bacteria. Drinking water and avoiding tobacco or excessive alcohol consumption can promote a healthier mouth.

A simple step for lifelong brain health

The link between oral health and Alzheimer’s highlights just how important it is to take care of your gums. By preventing gum disease and keeping harmful bacteria like P. gingivalis under control, you’re not just protecting your smile—you’re potentially defending your brain against cognitive decline.

If you’re concerned about your oral health and its impact on overall well-being, book an oral pathogen screening today. Early detection and prevention could be a vital step towards preserving your memory and your future.

About the author

Dr. Sonny Lee

Dr. Sonny Lee is the principal dentist at Leeming Dental, renowned for his expertise in preventative care, advanced diagnostics, and restorative treatments. He takes a patient-centred approach, combining years of experience with the latest technology to deliver high-quality, personalised care.

Dr. Sonny is passionate about early detection and disease prevention, utilising cutting-edge diagnostics like Oral Pathogen Testing to identify harmful bacteria and reduce the risk of both oral and systemic health issues. Committed to patient education, he empowers individuals with the knowledge and tools needed to achieve long-term oral wellness and overall well-being.

Dr Sonny Lee